Shengyuan Peptides

Catalog / GLP-1 & Metabolic Research / Retatrutide

Retatrutide research peptide — GLP-1 & Metabolic Research

Retatrutide

Triple-agonist research peptide targeting GLP-1, GIP, and glucagon receptors, used to study integrated metabolic signaling and energy balance regulation.

CAS Number2381089-83-2
Molecular Weight4731.4 Da
Purity99.2% (HPLC / MS verified)
CategoryGLP-1 & Metabolic Research
Quality metricsHPLC purity, peptide content, and identity are reported separately on the batch COA — see the purity guide.
StorageStore the lyophilized powder at -20°C in a dry, light-protected container; allow it to reach room temperature before opening to prevent condensation.
Research use only. Not for human or veterinary use. We do not provide dosing guidance or medical advice.
Request a Quote View Batch COA Data

About Retatrutide

Retatrutide is a synthetic multi-receptor agonist peptide engineered to engage the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors simultaneously. Its design places it in the incretin-mimetic structural class, with a backbone and fatty-acid conjugation pattern suited to prolonged receptor interaction in experimental systems. Because it activates three signaling axes at once, it is of interest for research into how combined incretin and glucagon signaling coordinates energy intake, glucose handling, lipid oxidation, and body-composition outcomes in preclinical models. Investigators use it to map receptor crosstalk, downstream cAMP pathways, and tissue-specific responses across pancreas, liver, and adipose tissue. Purity is critical here: trace truncation or deamidation products can shift receptor selectivity and confound dose-response data, so Shandong Shengyuan verifies each batch by RP-HPLC, LC-MS identity confirmation, and peptide-content assay before release. All material is supplied lyophilized for research use only and is not intended for human or veterinary applications.

Research Applications

  • GLP-1, GIP, and glucagon receptor pharmacology
  • Energy expenditure and body-composition models
  • Nutrient-stimulated hormone secretion studies
  • Incretin signaling crosstalk assays
  • Preclinical metabolic disease research

Quality & Documentation

Every batch of Retatrutide is manufactured under our documented quality system and released with a Certificate of Analysis covering HPLC purity, mass spectrometry identity, peptide content, water content, and endotoxin. The batch code on your vial can be verified online in the COA lookup section of this site.

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