Shengyuan Peptides

Catalog / GH Axis Peptides / Sermorelin Acetate

Sermorelin Acetate research peptide — GH Axis Peptides

Sermorelin Acetate

Synthetic GHRH(1–29) analogue for investigating pituitary growth hormone release and GH/IGF-1 axis regulation in preclinical research.

CAS Number86168-78-7
Molecular Weight3357.9 Da
Purity99.3% (HPLC / MS verified)
CategoryGH Axis Peptides
SequenceYADAIFTNSYRKVLGQLSARKLLQDIMSR
Quality metricsHPLC purity, peptide content, and identity are reported separately on the batch COA — see the purity guide.
StorageKeep lyophilized powder at -20°C in a moisture-barrier container; reconstituted aliquots should be kept cold and used promptly.
Research use only. Not for human or veterinary use. We do not provide dosing guidance or medical advice.
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About Sermorelin Acetate

Sermorelin is a synthetic peptide comprising the first 29 amino acids of growth hormone-releasing hormone (GHRH), the minimal sequence that retains receptor-activating capability at the pituitary GHRH receptor. Supplied as an acetate salt, it offers favorable handling and solubility characteristics for laboratory formulation work. Researchers use sermorelin as a reference agonist in assays of growth hormone (GH) secretion, to characterize GHRH-receptor pharmacology, and to study how GH pulsatility feeds back on hepatic IGF-1 production and downstream metabolic pathways. Because receptor engagement maps to specific residues within the 1–29 region, sequence deletions, oxidation of methionine, or deamidation can reduce potency measurably; chromatographically invisible impurities are a known source of assay variability. Shandong Shengyuan addresses this through RP-HPLC purity certification at 99.3% or higher, LC-MS sequence and mass confirmation, and peptide-content normalization so that reported concentrations reflect active peptide rather than salt and moisture. For research use only; not intended for human or veterinary use.

Research Applications

  • GHRH receptor pharmacology
  • Growth hormone release assays
  • IGF-1 axis studies
  • Pituitary cell signaling research
  • Preclinical metabolic studies

Quality & Documentation

Every batch of Sermorelin Acetate is manufactured under our documented quality system and released with a Certificate of Analysis covering HPLC purity, mass spectrometry identity, peptide content, water content, and endotoxin. The batch code on your vial can be verified online in the COA lookup section of this site.

Related Products

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