About KPV
KPV (Lys-Pro-Val) is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone, a minimal sequence investigated for anti-inflammatory effects in cellular models while lacking the melanotropic activity of the parent hormone. Its small size makes it a practical tool for studying how short peptides modulate inflammatory signaling in intestinal epithelial cells, immune cells, and preclinical models of colitis or barrier dysfunction. Researchers also employ KPV in structure-activity studies that map which elements of alpha-MSH contribute to specific receptor-independent responses. For a tripeptide, quality control centers on coupling completeness and salt form: deletion peptides such as Lys-Pro or Pro-Val, residual trifluoroacetate, and counter-ion mismatches can skew cell-based assays and solubility behavior. Shandong Shengyuan produces KPV under controlled solid-phase conditions and releases material only after RP-HPLC purity of 99.3% or higher, LC-MS mass confirmation, and quantitative peptide-content analysis. The lyophilized product is intended for research use only, not for human or veterinary use.
Research Applications
- Intestinal epithelial barrier research
- Inflammatory signaling assays
- Colitis and gut inflammation models
- Alpha-MSH structure-activity studies
- Immune cell cytokine research
Quality & Documentation
Every batch of KPV is manufactured under our documented quality system and released with a Certificate of Analysis covering HPLC purity, mass spectrometry identity, peptide content, water content, and endotoxin. The batch code on your vial can be verified online in the COA lookup section of this site.
TB-500 
BPC157 
BBKG80